Detalhe da pesquisa
1.
Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity.
Nat Immunol
; 24(2): 267-279, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36543958
2.
Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion.
Nat Immunol
; 22(2): 205-215, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33398183
3.
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.
Immunity
; 45(2): 374-88, 2016 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-27496732
4.
TACI haploinsufficiency protects against BAFF-driven humoral autoimmunity in mice.
Eur J Immunol
; 51(9): 2225-2236, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34146342
5.
The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction.
Immunity
; 45(3): 701-703, 2016 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-27653602
6.
Cutting Edge: BAFF Overexpression Reduces Atherosclerosis via TACI-Dependent B Cell Activation.
J Immunol
; 197(12): 4529-4534, 2016 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27837104
7.
Cutting Edge: BAFF Promotes Autoantibody Production via TACI-Dependent Activation of Transitional B Cells.
J Immunol
; 196(9): 3525-31, 2016 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27022196
8.
B-cell intrinsic TLR7 signals promote depletion of the marginal zone in a murine model of Wiskott-Aldrich syndrome.
Eur J Immunol
; 45(10): 2773-9, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26256668
9.
Opposing impact of B cell-intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation.
J Immunol
; 192(10): 4525-32, 2014 May 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24711620
10.
Functional Diversity of Memory CD8 T Cells is Spatiotemporally Imprinted.
bioRxiv
; 2024 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38585842
11.
Lessons for the Next Generation of Scientists from the Second Annual Arthur and Sandra Irving Cancer Immunology Symposium.
Cancer Immunol Res
; 11(12): 1571-1577, 2023 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37906619
12.
Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells.
Sci Immunol
; 7(74): eabj9123, 2022 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35930654
13.
CD8+ T cell metabolism in infection and cancer.
Nat Rev Immunol
; 21(11): 718-738, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33981085
14.
Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells.
J Clin Invest
; 131(7)2021 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33792560
15.
Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection.
J Exp Med
; 218(8)2021 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34037670
16.
IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell.
Cancer Immunol Res
; 7(8): 1258-1266, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31239318
17.
4-1BB costimulation induces T cell mitochondrial function and biogenesis enabling cancer immunotherapeutic responses.
J Exp Med
; 215(4): 1091-1100, 2018 04 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29511066
18.
Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions.
Cell Rep
; 22(6): 1509-1521, 2018 02 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29425506
19.
Efficacy of PD-1 Blockade Is Potentiated by Metformin-Induced Reduction of Tumor Hypoxia.
Cancer Immunol Res
; 5(1): 9-16, 2017 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27941003
20.
Tumor Microenvironment Metabolism: A New Checkpoint for Anti-Tumor Immunity.
Vaccines (Basel)
; 4(4)2016 Dec 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27929420